One of the major problems I see in many religious systems is the propensity for self esteem abasement. Hating the perceived imperfections present in the human condition becomes a precondition for entrance into the religious order, and the subsequent destruction of confidence produces a need to alleviate chronic anxiety.
Unscrupulous manipulators realize that dominating people becomes much easier where self loathing resides, but the side effects of a self-destructive mindset pose a significant problem. Thus, internalized individual abhorrence is directed outwards towards an endless parade of enemies, diverting the attention from the real problem; a lack of self acceptance and love.
Sometimes, the reluctance to face our own despised characteristics spawns the most virulent animosity toward others who display them. The reflection of our own imperfections arouse a violent revulsion; as if smashing the mirror can cure us of the traits we find repulsive.
I believe that many in the gender divergent community have struggled to obtain a realistic and compassionate understanding of themselves, and therefore have much to offer the misguided in respect to the importance of acceptance and empathy.
A house divided against itself can not stand, no matter how many props of hatred try and support it; perhaps only a foundation of loving embracement can build the people that our fractured and fracas-loving society requires.